Laboratory of Metallic Biomaterials


Research Center on Materials Engineering – CECIM

(Centrul de cercetare în ingineria materialelor)

Faculty of Materials Science and Engineering,

Gheorghe Asachi Technical University of Iasi


Publications in the field of biocompatible materials


A.  Books

1.    Minciună M.G., Vizureanu P., Materiale metalice avansate pentru aplicații medicale, Ed. PIM, Iași, 2016, 178pg., ISBN 978-606-13-3529-9.

2.    Baltatu M.S., Vizureanu P., Materiale Biocompatibile, Ed. PIM, 2019, 146 p., ISBN 978-606-13-5168-8

3.    Minciuna M.G., Vizureanu P., Baltatu M.S., Sisteme Moderne Pentru Aplicații Medicale, Ed. PIM, 2022, 135 p.

4.    Vizureanu P., Baltatu M.S., Titanium-Based Alloys for Biomedical Applications, Materials Research Forum LLC, volume 74, 2020, ISBN 978-1-78984-465-8, DOI 10.5772/intechopen.91906.

5.    Burduhos-Nergis D.P., Burduhos-Nergis D.D., Baltatu M.S., Vizureanu P., Advanced Coatings for the Corrosion Protection of Metals, Materials Research Foundations, Vol 115, 2022, ISBN 978-1-64490-166-3, doi: 10.21741/9781644901670

6.    Baltatu M.S., Burduhos-Nergis D.D., Burduhos-Nergis D.P., Vizureanu P., Advanced Metallic Biomaterials, Materials Research Foundations, Vol. 118, 2022, Print ISBN 978-1-64490-176-2, DOI: 10.21741/9781644901779

7.    Minciuna M.G., Vizureanu P., Baltatu M.S., Sisteme Moderne Pentru Aplicații Medicale, Ed. PIM, 2022, 135p.

8.    Vizureanu, P., (editor), Special Issue Future Trends in Advanced Materials and Processes, Materials, ISBN 978-3-0365-6470-8, Published: February 2023, Pages: 352

9.    Vizureanu, P. (editor), Botelho C.M.D.C.F.- co-editor, Biomaterials, Intech Open, 2020, ISBN: 978-1-78984-465-8, DOI: 10.5772/intechopen.87369


B. Chapters in International books

1.      Vizureanu P., Bălțatu M.S., Sandu A.V., Development of New Advanced Ti-Mo Alloys for Medical Applications, in Biomaterials, IntechOpen, 2020 DOI:

2.      Vizureanu P., Bălțatu M.S., Sandu A.V., Achitei D.C., Burduhos Nergis D.D., Perju M.C., New Trends in Bioactive Glasses for Bone Tissue: A review, in Current Concepts in Dental Implantology - From Science to Clinical Research, IntechOpen, 2021, DOI:

3.       Petrică Vizureanu, Mirabela Georgiana Minciuna, Gianina Iovan and Simona Stoleriu, Synthesis, Processing and Characterization of the Cobalt Alloys with Silicon Addition, in Cobalt, IntechOpen, p. 23-48, 2018. DOI: 10.5772/intechopen.70886


C. Scientific Articles

1.    Benea, L., Ravoiu Lupu, A., Bounegru, I., Vizureanu, P. Effect of Functional Nanoporous TiO2 Film Obtained on Ti6Al4V Implant Alloy to Improve Resistance in Biological Solution for Inflammatory Conditions. International Journal of Molecular Sciences, 2023, 24, 8529.

2.    D.-P. Burduhos-Nergis, A.V. Sandu, D.-D. Burduhos-Nergis, P. Vizureanu, C. Bejinariu, Phosphate Conversion Coating – A Short Review, Archives of Metallurgy and Materials. 68 (2023), 3, 1029-1034, DOI:

3.    Baltatu, M.S., Vizureanu, P., Sandu, A.V., Solcan, C., Hritcu, L.D., Spataru, M.C. Research Progress of Titanium-Based Alloys for Medical Devices. Biomedicines 2023, 11, 2997.

4.    Jiménez-Marcos C, Mirza-Rosca JC, Baltatu MS, Vizureanu P. Evaluation of New Titanium Alloys as Potential Materials for Medical Devices. Microscopy and Microanalysis 2023 Jul 22,29(Supplement_1):196-201. doi: 10.1093/micmic/ozad067.088.

5.    Jimenez-Marcos, C., Mirza-Rosca, J.C., Baltatu, M.S., Vizureanu, P. Effect of Si Contents on the Properties of Ti15Mo7ZrxSi Alloys. Materials 2023, 16, 4906.

6.    Ramli, M.I.I., Salleh, M.A.A.M., Abdullah, M.M.A.B., Zaimi, N.S.M., Sandu, A.V., Vizureanu, P., Rylski, A., Amli, S.F.M. Formation and Growth of Intermetallic Compounds in Lead-Free Solder Joints: A Review. Materials 2022, 15, 1451.

7.    Baltatu, M.S., Chiriac-Moruzzi, C., Vizureanu, P., Tóth, L., Novák, J. Effect of Heat Treatment on Some Titanium Alloys Used as Biomaterials. Applied Sciences 2022, 12, 11241.

8.    Arokiasamy, P, Abdullah, MMA, Abd Rahim, SZ, Luhar, S, Sandu, AV, Jamil, NH, Nabialek, M., Synthesis methods of hydroxyapatite from natural sources: A review, CERAMICS INTERNATIONAL, 2022, 48, 11, 14959-14979, 10.1016/j.ceramint.2022.03.064

9.    Perju, MC, Nejneru, C, Vizureanu, P, Aelenei, AA, Sandu, AV, Sachelarie, L, Nabialek, M. Some Aspects Concerning Titanium Coverage with Hydroxyapatite. Archives of Metallurgy and Materials 2022, 67(2), 521-527. DOI:

10. Voiculescu, I, Geanta, V, Chereches, T, Vizureanu, P, Stefanoiu, R, Rotariu, A, Mitrica, D., Impact Behavior of the Ballistic Targets Package Composed Of Dyneema Polymer And High Entropy Alloy Structures. Archives Of Metallurgy And Materials 2022, 67(2), 569-576. DOI:

11. Jimenez-Marcos, C., Mirza-Rosca, J.C., Baltatu, M.S., Vizureanu, P. Experimental Research on New Developed Titanium Alloys for Biomedical Applications. Bioengineering 2022, 9, 686.

12. Muhammad Nadzri, N.I., Halin, D.S.C., Al Bakri Abdullah, M.M., Joseph, S., Mohd Salleh, M.A.A., Vizureanu, P., Burduhos-Nergis, D.-P., Sandu, A.V., High-Entropy Alloy for Thin Film Application: A Review. Coatings 2022, 12, 1842. coatings12121842

13. Achitei, D.C., Baltatu, M.S., Vizureanu, P., Sandu, A.V., Benchea, M., Istrate, B., Ni-Cr Alloys Assessment for Dental Implants Suitability, Applied Sciences 2022, 12, 12814.

14. Jiménez-Marcos C., Baltatu M.S., Florido-Suárez N.R., Socorro-Perdomo P.P., Vizureanu P., Mirza-Rosca J.C. Mechanical properties and corrosion resistance of two new titanium alloys for orthopaedics applications, Materials Today: Proceedings, 2022.

15. Baltatu, I., Sandu, A.V., Vlad, M.D., Spataru, M.C., Vizureanu, P., Baltatu, M.S. Mechanical Characterization and In Vitro Assay of Biocompatible Titanium Alloys. Micromachines 2022, 13, 430.

16. Baltatu I., Sandu A.V., Baltatu M.S., Benchea M., Achitei D.C., Perju M.C., Vizureanu P., Benea L., Structural and Physical Characterization of New Ti-Based Alloys, Archives Of Metallurgy And Materials 67 (2022), 1, 255-259, DOI:

17. Spataru M.C, Cojocaru F.D., Sandu A.V., Solcan C., Duceac I.A., Baltatu M.S., Voiculescu I., Geanta V., Vizureanu P. Assessment of the Effects of Si Addition to a New TiMoZrTa System. Materials 2021, 14, 7610.

18. Baltatu, M.S., Sandu, A.V., Nabialek, M., Vizureanu, P. Biomimetic Deposition of Hydroxyapatite Layer on Titanium Alloys. Micromachines 2021, 12, 1447. .

19. Baltatu M.S., Spataru M.C., Verestiuc l., Balan V., Solcan C., Sandu A.V., Geanta V., Voiculescu I., Vizureanu P., Design, Synthesis, and Preliminary Evaluation for Ti-Mo-Zr-Ta-Si Alloys for Potential Implant Applications, Materials 2021, 14(22), 6806,

20. Baltatu M.S., Vizureanu P., Sandu A.V., Florido-Suarez N., Saceleanu M.V., Mirza-Rosca J.C., New Titanium Alloys, Promising Materials for Medical Devices, Materials 2021, 14(20), 5934,

21. Spataru M.C., Butnaru M., Sandu A.V., Vulpe V., Vlad M.D., Baltatu M.S., Geanta V., Voiculescu I., Vizureanu P., Solcan C., In-depth Assessment of New Ti-based Biocompatible Materials, Materials Chemistry and Physics 2021, 258, art 123959.

22. Verestiuc L., Spataru M.C., Baltatu M.S., Butnaru M., Solcan C., Sandu A.V., Voiculescu I., Geanta V., Vizureanu P., New Ti-Mo-Si materials for bone prosthesis applications, Journal of the Mechanical Behavior of Biomedical Materials 2021, 113, art 104198.

23. Baltatu, M.S., Vizureanu, P., Sandu, A.V., Munteanu, C., Istrate, B., Microstructural Analysis and Tribological Behavior of Ti-Based Alloys with a Ceramic Layer Using the Thermal Spray Method, Coatings 2020, 10, 12, art 1216, 2020.

24. Vizureanu, P., Yamaguchi, S., Le, P.T.M., Baltatu, M.S. Biocompatibility Evaluation of New TiMoSi Alloys, Acta Physica Polonica A, 2020, 138, 2, 283-286. DOI: 10.12693/APhysPolA.138.283.

25. Savin, A., Craus, M.L., Bruma, A., Novy, F., Malo, S., Chlada, M., Steigmann, R., Vizureanu, P., Harnois, C., Turchenko, V., Prevorovsky, Z. Microstructural Analysis and Mechanical Properties of TiMo20Zr7Ta15Six Alloys as Biomaterials. Materials 2020, 13, 4808.

26. Perju, M.C., Sandu, A.V., Vizureanu, P., Nejneru, C., Tugui, C.A., Burduhos-Nergis, D.D., Microstructural Analysis of Ti/W/WC Deposition by ESD Method, Acta Physica Polonica A, 2020, 138, 2, 214-217.

27. Savin, A., Craus, M.L., Bruma, A., Novy, F., Minarik, P., Jabor, M., Malo, S., Steigmann, R., Vizureanu, P., Harnois, C., Turchenko, V., Material properties mapping using complementary methods in titanium alloys TiMoSi used in medical application, Low-Dimensional Materials And Devices 2020, Proceedings of SPIE, Volume: 11465, Article Number: 114650Z, Published: 2020.

28.  Baltatu M.S., Tugui C.A., Perju M.C., Benchea M., Spataru M.C., Sandu A.V., Vizureanu P., Biocompatible Titanium Alloys used in Medical Applications, Revista de Chimie (Bucharest) 2019, 70, 4, pag. 1302-1306.

29.  Sandu A.V., Baltatu M.S., Nabialek M., Savin A., Vizureanu P., Characterization and Mechanical Proprieties of New TiMo Alloys Used for Medical Applications, Materials 2019, 12(18), 2973.

30.  Araoyinbo, A. O., Abdullah, M. M. A. B., Rahmat, A., Azmi, A. I., Vizureanu, P., Abd Rahim, W. M. F. Wan, Preparation of Heat Treated Titanium Dioxide (TiO2) Nanoparticles for Water Purification, IOP Conference Series-Materials Science and Engineering 2018, 374, Article Number: UNSP 012084. doi: 10.1088/1757-899X/374/1/012084

31.  Savin A., Vizureanu P., Prevorovsky Z., Chlada M., Krofta J., Baltatu M.S., Istrate B., Steigmann R., Noninvasive Evaluation of Special Alloys for Prostheses Using Complementary Methods, IOP Conference Series-Materials Science and Engineering 2018, 374, Article Number 012030.

32.  Baltatu, M. S., Vizureanu P., Balan T., Lohan M., Tugui C. A., Preliminary Tests for Ti-Mo-Zr-Ta Alloys as Potential Biomaterials, IOP Conference Series-Materials Science and Engineering 2018, 374, UNSP 012023.

33.  Baltatu M. S., Vizureanu P., Geanta V., Nejneru C., Tugui C. A., Focsaneanu S. C., Obtaining and Mechanical Properties of Ti-Mo-Zr-Ta Alloys, Book Series: IOP Conference Series-Materials Science and Engineering, Volume: 209, Article Number: 012019, 2017.

34. Bălțatu M.S., Vizureanu P., Cimpoeșu R., Abdullah M.M.A.B., Sandu A.V., The Corrosion Behavior of TiMoZrTa Alloys Used for Medical Applications, Revista de Chimie 2016, vol. 67, nr. 10, 2016, pp. 2100-2102.

35.  Bălțatu M.S., Vizureanu P., Mareci D., Burtan L.C., Chiruță C., Trincă L.C., Effect of Ta on the electrochemical behavior of new TiMoZrTa alloys in artificial physiological solution simulating in vitro inflammatory conditions, Materials and Corrosion-Werkstoffe und Korrosion 2016, vol. 67 , nr. 12, 2016, pp. 1314-1320.

36. Baltatu, I., Benea L., Vizureanu P., Baltatu M.S., Nabialek M., Biofunctionalization Of Titanium Alloys: Methods And Applications, European Journal Of Materials Science And Engineering 2023, Volume 8, Issue 4, 240-248, DOI: 10.36868/ejmse.2023.08.04.240

37.  Baltatu M.S., Vizureanu P., Sandu A.V., Baltatu I., Burduhos-Nergis D.D., Benchea M., Prospects On Titanium Biomaterials, European Journal Of Materials Science And Engineering 2023, Volume 8, Issue 4, 201-212, DOI: 10.36868/ejmse.2023.08.04.201

38. Bălțatu M. S., Vizureanu P., Bălțatu I., Burduhos Nergis D.D., Achitei D.C., Perju M.C., Electrochemical Behaviour of Ti-Mo Alloys for Medical Application in Biological Solution, IOP Conference Series: Materials Science and Engineering 877 (2020) 012031, IOP Publishing, doi:10.1088/1757-899X/877/1/012031.

39. Bălţatu M.S., Vizureanu P., Goanţă V., Tugui C.A., Voiculescu I., Mechanical tests for Ti-based alloys as new medical materials, IOP Conference Series: Materials Science and Engineering 572, 2019, 012029.

40. Baltatu I., Vizureanu P., Baltatu M.S., Achitei D., Nabialek M., Structural Analysis Of Ti-Mo Alloys, European Journal Of Materials Science And Engineering, Vol. 4, Issue 1, 2019, PP. 44-50.

41. Bălţatu I., Vizureanu P., Ciolacu F., Achiţei D.C., Bălţatu M.S., Vlad D., In Vitro study for new Ti-Mo-Zr-Ta alloys for medical use, IOP Conference Series: Materials Science and Engineering 2019, 572, 012030.

42. Vasilescu V.G., Sandu I., Nemtoi G., Sandu A.V., Popescu V., Vasilache V., Sandu I.G., Vasilescu E., The reactivity of Ti10Zr alloy in biological and electrochemical systems in the presence of chitosan, RSC ADVANCES 2017, 7, 23, p. 13919-13927.

43. Minciuna M.G., Vizureanu P., Abdullah M.M.B., Achitei D. C., Istrate B., Cimpoesu R., Focsaneanu S.C., Surface Characterization of New Biomaterials, Book Series: IOP Conference Series: Materials Science and Engineering, 2017, 209, Article Number: 012022. DOI: 10.1088/1757-899X/209/1/012022

44. Bălțatu M. S., Vizureanu P., Benchea M., Minciună M.G., Achiței A.C., Istrate B., Ti-Mo-Zr-Ta Alloy for Biomedical Applications: Microstructures and Mechanical Properties, Key Engineering Materials 2017, 750, pp 184-188.

45. Minciună M.G., Vizureanu P, Achitei D.C., Sandu A.V., The advanced characterization of new alloy by Co-Cr-Mo system, Journal of Optoelectronics and Advanced Materials 2016, Vol. 18, No. 7-8, p. 717-722.

46. Minciuna, MG, Vizureanu, P., Mares, M, Nastasa, V, Achitei, DC, Sandu, AV, Biocompatibility Study of CoCrMoSik Original Alloy Variants, Revista de Chimie 2016, Volume: 67, Issue: 2, Pages: 362-365.

47. Minciuna, MG, Vizureanu, P, Achitei, DC, Sandu, AV, Berbecaru, A, Sandu, IG, Structural characterization and properties analysis of CoCrMoSi Alloys, Journal Of Optoelectronics And Advanced Materials, 2016, Volume: 18, Issue: 1-2, Pages: 174-178.

48. Minciuna M.G., Vizureanu P., Hanganu C., Achitei D.C., Popescu D.C., Focsaneanu S.C., The structural characterization of some biomaterials, type AISI 310, used in medicine, IOP Conference Series-Materials Science and Engineering, 2016, Volume: 133 Article Number: UNSP 012019. DOI: 10.1088/1757-899X/133/1/012019

49. Bălţatu M.S., Vizureanu P., Ţierean M.H., Minciună M.G., Achiţei D.C., Ti-Mo Alloys used in medical applications, Advanced Materials Research 2015, 1128, pp. 105-111.

50. Bălţatu M.S., Vizureanu P., Istrate B., Physical and structural characterization of Ti-based alloy, International Journal of Modern Manufacturing Technologies, 2015, Vol. VII, No. 2, pp.12-17.

51. Bălțatu M.S., Cimpoeșu R., Vizureanu P., Achitei D.C., Minciuna M.G., Microstructural characterization of TiMoZrTa alloy, The Annals of „Dunărea de Jos” University of Galaţi, Fascicle IX. Metallurgy and Materials Science, 2015, nr. 4, pp. 23-26.

52. Stirbu, I, Vizureanu, P, Cimpoesu, R, Dascalu, G, Gurlui, SO, Bernevig, M, Benchea, M, Cimpoesu, N, Postolachee, P, Advanced metallic materials response at laser excitation for medical applications, Journal Of Optoelectronics And Advanced Materials, 2015, Volume: 17, Issue: 7-8, Pages: 1179-1185/

53. Popescu D., Vizureanu P., Minciuna, MG, Veliceasa, B. Alexa, O, Risk factors of titanium locking plate osteosynthesis, E-Health And Bioengineering Conference (EHB), 2015. DOI: 10.1109/EHB.2015.7391364

54. Stirbu, I., Vizureanu, P., Cimpoesu, N., Cimpoesu, R., Benchea, M, Implant Material for Sports Injuries, Edited by: Stanescu, M, Paunescu, M, 4th International Congress Of Physical Education, Sport And Kinetotherapy (ICPESK 2014), 2015, Pages: 169-174.

55. Minciuna, MG, Vizureanu, P, Geanta, V, Voiculescu, I, Sandu, AV, Achitei, DC, Vitalariu, AM, Effect of Si on the Microstructure and Mechanical Properties of Biomedical CoCrMo Alloy, Revista De Chimie 2015, Volume: 66, Issue: 6, Pages: 891-894

56. Minciuna, MG, Vizureanu, P., Achitei, DC, Ghiban, B, Sandu, AV, Mareci, D, Balan, A, Electrochemical Behaviour of CoCrMo and CoCrMoSi5 alloys at Different Simulated Physiological Medium, Revista De Chimie 2014, Volume: 65, Issue: 10, Pages: 1138-1141

57. Minciuna, MG, Vizureanu, P, Achitei, DC, Ghiban, N, Sandu, AV, Forna, NC, Structural Characterization of Some CoCrMo Alloys with Medical Applications, Revista De Chimie 2014, Volume: 65, Issue: 3, Pages: 335-338

58. Stirbu, I., Vizureanu, P., Cimpoesu, R., Lungu, M., Bernevig, M., Popa, R.F., Chemical procedures for Ti-alloy based metallic surface modification, Optoelectronics And Advanced Materials-Rapid Communications, 2014, Volume: 8, Issue: 3-4, Pages: 242-246.

59. Sandu, AV, Bejinariu, C, Nemtoi, G, Sandu, IG, Vizureanu, P, Ionita, I, Baciu, C, New Anticorrosion Layers Obtained by Chemical Phosphatation, Revista De Chimie 2013, Volume: 64, Issue: 8, Pages: 825-827.

60. Stirbu, I, Vizureanu, P, Ratoi, M, Cimpoesu, N, Electrochemical Deposition of Hydroxyapatite (RA) on Titanium Alloys for the Implant Surface Bio-functionalization, IEEE, 2013 Ehealth And Bioengineering Conference (EHB), 2013.

61. Stirbu I., Vizureanu, P, Ratoi, M, Cimpoesu, R, Obtaining Hydroxyapatite (HA) by Sol-Gel Method on Ti6Al4V Alloys Aiming the Implant's Surface Bio-Functionalization, IEEE, 2013 Ehealth And Bioengineering Conference (EHB), 2013.

62. M.G. Minciună, P. Vizureanu, A.A. Minea, D.C. Achiţei, Engineering biocompatible implant surface, Analele Universității Dunărea de Jos din Galați, XXXI, 2013, Special Issue, p. 97- 99.

63. Hanganu, SC, Armencia, AO, Grigoras, S., Vizureanu, P., Tribological Comparative Study on Two Composite Materials for Restorative Dental Applications in Smoking Affected Teeth, Materiale Plastice, 2010, 47, 3, Pages: 375-378 Published: 2010.

64. Ciobanu G., Carja G., Ciobanu O., Sandu I., Sandu A., SEM and EDX studies of bioactive hydroxyapatite coatings on titanium implants, in MICRON 2009, 40, (1), p. 143-156.